The carboxylation of propionic acid by liver mitochondria.
نویسندگان
چکیده
The glycogenic effect of propionic acid (1, 2) results from the conversion of propionate carbon into carbohydrate (3, 4) and not from an indirect stimulation of carbohydrate production from other sources. The finding (5,6) that extracts of mitochondria can convert propionate and bicarbonate to an organic acid identified as succinic acid (6) provided an explanation for this glycogenic effect. The present study with intact mitochondria aims to ascertain the physiological significance of the carboxylation reaction which had been found to occur in soluble extracts.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 219 2 شماره
صفحات -
تاریخ انتشار 1956